AMD Instinct MI350X vs NVIDIA A2 — GPU Comparison (Jul 2026)

AMD Instinct MI350X (288GB HBM3e, 1,800 TFLOPS FP16, CDNA 4) vs NVIDIA A2 (16GB GDDR6, 18 TFLOPS FP16, Ampere). Cloud pricing: NVIDIA A2 from $0.22/hr. Compare specs, VRAM, performance, and pricing across 1 cloud providers to find the best GPU for your AI workload.

Bottom Line: AMD Instinct MI350X vs NVIDIA A2

AMD Instinct MI350X comes out ahead overall, leading in 5 of 6 compared categories.

Where AMD Instinct MI350X leads

  • FP16 (1,800 TFLOPS vs 18 TFLOPS)
  • VRAM (288 GB vs 16 GB)
  • Memory Bandwidth (8,000 GB/s vs 200 GB/s)
  • FP32 (72 TFLOPS vs 4.5 TFLOPS)
  • Release Year (2025 vs 2021)

Where NVIDIA A2 leads

  • TDP (60W vs 1000W)

Choose AMD Instinct MI350X for Next-gen AI training, inference at scale. Choose NVIDIA A2 for Edge inference, entry-level AI.

Frequently Asked Questions

Is AMD Instinct MI350X or NVIDIA A2 better?
AMD Instinct MI350X leads in 5 of 6 compared categories. The right choice still depends on the factors that matter most to you.
Which has a better FP16, AMD Instinct MI350X or NVIDIA A2?
AMD Instinct MI350X (1,800 TFLOPS vs 18 TFLOPS).
Which has a better VRAM, AMD Instinct MI350X or NVIDIA A2?
AMD Instinct MI350X (288 GB vs 16 GB).
AMD Instinct MI350X vs NVIDIA A2 — GPU Comparison (Jul 2026)
AMD Instinct MI350X
288GB HBM3e · CDNA 4
View AMD Instinct MI350X Pricing
NVIDIA A2
16GB GDDR6 · Ampere
View NVIDIA A2 Pricing
Specifications
Manufacturer AMD NVIDIA
Architecture CDNA 4 Ampere
VRAM 288 GB HBM3e 16 GB GDDR6
Memory Bandwidth 8,000 GB/s 200 GB/s
FP16 (Tensor) 1800.0 TFLOPS 18.0 TFLOPS
FP32 72.0 TFLOPS 4.5 TFLOPS
TDP 1000W 60W
Release Year 2025 2021
Segment Data center Data center
Best For Next-gen AI training inference at scale Edge inference entry-level AI
Cloud Pricing
Cheapest On-Demand $0.22/hr
Cheapest Spot
Providers 1 1
Provider Pricing (On-Demand)
Cherry Servers N/A $0.22/hr
AMD Instinct MI350X NVIDIA A2