AMD Instinct MI325X vs NVIDIA GB200 Superchip — GPU Comparison (Jul 2026)
AMD Instinct MI325X (256GB HBM3e, 1,307 TFLOPS FP16, CDNA 3) vs NVIDIA GB200 Superchip (384GB HBM3e, 4,500 TFLOPS FP16, Blackwell). Cloud pricing: AMD Instinct MI325X from $2.00/hr. Compare specs, VRAM, performance, and pricing across 1 cloud providers to find the best GPU for your AI workload.
Bottom Line: AMD Instinct MI325X vs NVIDIA GB200 Superchip
NVIDIA GB200 Superchip comes out ahead overall, leading in 3 of 5 compared categories.
Where AMD Instinct MI325X leads
- FP32 (163.4 TFLOPS vs 150 TFLOPS)
- TDP (1000W vs 2700W)
Where NVIDIA GB200 Superchip leads
- FP16 (4,500 TFLOPS vs 1,307 TFLOPS)
- VRAM (384 GB vs 256 GB)
- Memory Bandwidth (16,000 GB/s vs 6,000 GB/s)
Choose AMD Instinct MI325X for AI training, large model inference. Choose NVIDIA GB200 Superchip for Largest-scale AI training, multi-trillion parameter models.
Frequently Asked Questions
Is AMD Instinct MI325X or NVIDIA GB200 Superchip better?
NVIDIA GB200 Superchip leads in 3 of 5 compared categories. The right choice still depends on the factors that matter most to you.
Which has a better FP16, AMD Instinct MI325X or NVIDIA GB200 Superchip?
NVIDIA GB200 Superchip (4,500 TFLOPS vs 1,307 TFLOPS).
Which has a better VRAM, AMD Instinct MI325X or NVIDIA GB200 Superchip?
NVIDIA GB200 Superchip (384 GB vs 256 GB).
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AMD Instinct MI325X
256GB HBM3e · CDNA 3
|
NVIDIA GB200 Superchip
384GB HBM3e · Blackwell
|
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|---|---|---|---|
| Specifications | |||
| Manufacturer | AMD | NVIDIA | |
| Architecture | CDNA 3 | Blackwell | |
| VRAM | 256 GB HBM3e | 384 GB HBM3e | |
| Memory Bandwidth | 6,000 GB/s | 16,000 GB/s | |
| FP16 (Tensor) | 1307.0 TFLOPS | 4500.0 TFLOPS | |
| FP32 | 163.4 TFLOPS | 150.0 TFLOPS | |
| TDP | 1000W | 2700W | |
| Release Year | 2024 | 2024 | |
| Segment | Data center | Data center | |
| Best For | AI training large model inference | Largest-scale AI training multi-trillion parameter models | |
| Cloud Pricing | |||
| Cheapest On-Demand | $2.00/hr | — | |
| Cheapest Spot | — | — | |
| Providers | 2 | 0 | |
| Provider Pricing (On-Demand) | |||
|
$2.00/hr | N/A | |
AMD Instinct MI325X
NVIDIA GB200 Superchip