AMD Instinct MI325X vs NVIDIA H200 SXM — GPU Comparison (Apr 2026)
AMD Instinct MI325X (256GB HBM3e, 1,307 TFLOPS FP16, CDNA 3) vs NVIDIA H200 SXM (141GB HBM3e, 990 TFLOPS FP16, Hopper). Cloud pricing: AMD Instinct MI325X from $2.00/hr, NVIDIA H200 SXM from $2.05/hr. Compare specs, VRAM, performance, and pricing across 4 cloud providers to find the best GPU for your AI workload.
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AMD Instinct MI325X
256GB HBM3e · CDNA 3
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NVIDIA H200 SXM
141GB HBM3e · Hopper
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| Specifications | |||
| Manufacturer | AMD | NVIDIA | |
| Architecture | CDNA 3 | Hopper | |
| VRAM | 256 GB HBM3e | 141 GB HBM3e | |
| Memory Bandwidth | 6,000 GB/s | 4,800 GB/s | |
| FP16 (Tensor) | 1307.0 TFLOPS | 990.0 TFLOPS | |
| FP32 | 163.4 TFLOPS | 67.0 TFLOPS | |
| TDP | 1000W | 700W | |
| Release Year | 2024 | 2024 | |
| Segment | Data center | Data center | |
| Best For | AI training large model inference | Large model training inference for 70B+ parameter models | |
| Cloud Pricing | |||
| Cheapest On-Demand | $2.00/hr | $2.05/hr | |
| Cheapest Spot | — | $3.59/hr | |
| Providers | 2 | 3 | |
| Provider Pricing (On-Demand) | |||
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$2.00/hr | N/A | |
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N/A | $2.05/hr | |
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N/A | $3.44/hr | |
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N/A | $3.59/hr | |
AMD Instinct MI325X
NVIDIA H200 SXM
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Top Providers for AMD Instinct MI325X and NVIDIA H200 SXM
These 3 providers offer both AMD Instinct MI325X and NVIDIA H200 SXM. Full head-to-head comparison of GPU models, pricing, infrastructure, and developer tools.
Vultr vs Vast.ai vs DigitalOcean - GPU Provider Comparison (April 2026)
Side-by-side comparison of Vultr vs Vast.ai vs DigitalOcean. Quickly compare GPU models, hourly pricing, spot instances, billing granularity, VRAM, regions, developer tools, Kubernetes support, and compliance to narrow down your cloud GPU provider shortlist. Data updated April 2026.
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Vultr
High-performance cloud GPU across 32 global regions
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Vast.ai
Instant GPUs. Transparent Pricing.
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DigitalOcean
Simple, scalable GPU cloud for AI/ML
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|---|---|---|---|
| Overview | |||
| Trustpilot Rating | 1.8 | 4.4 | 4.6 |
| Headquarters | United States | United States | United States |
| Provider Type | Multi-Cloud | GPU Marketplace | N/A |
| Best For | AI training inference video rendering HPC Stable Diffusion game development generative AI fine-tuning research | AI training inference fine-tuning Stable Diffusion batch processing research LLM serving generative AI | AI training inference fine-tuning LLM deployment LLM serving computer vision startups generative AI research |
| GPU Hardware | |||
| GPU Models | A16 A40 L40S A100 PCIe GH200 A100 SXM H100 SXM B200 B300 MI300X MI325X MI355X | B200 H200 H100 SXM H100 NVL A100 SXM A100 PCIe RTX 5090 RTX 5080 RTX 5070 Ti RTX 6000 Pro RTX 6000 Ada RTX 4500 Ada RTX A6000 RTX A5000 RTX A4000 L40S L40 A40 A10 RTX 4090 RTX 4080 RTX 4070 Ti RTX 4070 RTX 4060 Ti RTX 4060 RTX 3090 Ti RTX 3090 RTX 3080 Ti RTX 3080 RTX 3070 Ti RTX 3070 Tesla V100 Tesla T4 A2 GTX 1080 | RTX 4000 Ada RTX 6000 Ada L40S MI300X H100 SXM H200 |
| Max VRAM (GB) | 288 | 192 | 192 |
| Max GPUs/Instance | 16 | 8 | 8 |
| Interconnect | NVLink | NVLink, InfiniBand | NVLink |
| Pricing | |||
| Starting Price ($/hr) | $0.47/hr | $0.06/hr | $0.76/hr |
| Billing Granularity | Per-hour | Per-second | Per-second |
| Spot/Preemptible | Yes | Yes | No |
| Reserved Discounts | N/A | Up to 50% (1-6 month reserved) | N/A |
| Free Credits | Up to $300 free credit for 30 days | Small test credit on signup | $200 free credit for 60 days |
| Egress Fees | Standard (varies by plan) | Varies by host ($/TB) | None (included in plan) |
| Storage | 350 GB - 61 TB NVMe (included), Block Storage at $0.10/GB/mo, S3-compatible Object Storage | Varies by host ($/GB/hr, charged while instance exists) | 500-720 GiB NVMe boot (included), 5 TiB NVMe scratch on larger configs, Volumes at $0.10/GiB/mo |
| Infrastructure | |||
| Regions | 32 regions across 6 continents (Americas, Europe, Asia, Australia, Africa) | 500+ locations, 40+ data centers | New York (NYC2), Toronto (TOR1), Atlanta (ATL1), Richmond (RIC1), Amsterdam (AMS3) |
| Uptime SLA | 100% | No formal SLA (host reliability scores visible) | 99% |
| Developer Experience | |||
| Frameworks | PyTorch TensorFlow CUDA cuDNN ROCm Hugging Face NVIDIA NGC | PyTorch TensorFlow CUDA vLLM ComfyUI | PyTorch TensorFlow Jupyter Miniconda CUDA ROCm Hugging Face |
| Docker Support | Yes | Yes | Yes |
| SSH Access | Yes | Yes | Yes |
| Jupyter Notebooks | Yes | Yes | Yes |
| API / CLI | Yes | Yes | Yes |
| Setup Time | Minutes | Seconds | Minutes |
| Kubernetes Support | Yes | No | Yes |
| Business Terms | |||
| Min Commitment | None | None | None |
| Compliance | SOC 2+ (HIPAA) PCI ISO 27001 ISO 27017 ISO 27018 ISO 20000-1 CSA STAR Level 1 | SOC 2 Type 2 HIPAA GDPR CCPA | SOC 2 Type II SOC 3 HIPAA (with BAA) CSA STAR Level 1 |
Vultr
Vast.ai
DigitalOcean
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