AMD Instinct MI325X vs NVIDIA L40 — GPU Comparison (Jul 2026)
AMD Instinct MI325X (256GB HBM3e, 1,307 TFLOPS FP16, CDNA 3) vs NVIDIA L40 (48GB GDDR6, 181 TFLOPS FP16, Ada Lovelace). Cloud pricing: AMD Instinct MI325X from $2.00/hr. Compare specs, VRAM, performance, and pricing across 1 cloud providers to find the best GPU for your AI workload.
Bottom Line: AMD Instinct MI325X vs NVIDIA L40
AMD Instinct MI325X comes out ahead overall, leading in 5 of 6 compared categories.
Where AMD Instinct MI325X leads
- FP16 (1,307 TFLOPS vs 181 TFLOPS)
- VRAM (256 GB vs 48 GB)
- Memory Bandwidth (6,000 GB/s vs 864 GB/s)
- FP32 (163.4 TFLOPS vs 90.5 TFLOPS)
- Release Year (2024 vs 2023)
Where NVIDIA L40 leads
- TDP (300W vs 1000W)
Choose AMD Instinct MI325X for AI training, large model inference. Choose NVIDIA L40 for Inference, video processing, rendering.
Frequently Asked Questions
Is AMD Instinct MI325X or NVIDIA L40 better?
AMD Instinct MI325X leads in 5 of 6 compared categories. The right choice still depends on the factors that matter most to you.
Which has a better FP16, AMD Instinct MI325X or NVIDIA L40?
AMD Instinct MI325X (1,307 TFLOPS vs 181 TFLOPS).
Which has a better VRAM, AMD Instinct MI325X or NVIDIA L40?
AMD Instinct MI325X (256 GB vs 48 GB).
|
AMD Instinct MI325X
256GB HBM3e · CDNA 3
|
NVIDIA L40
48GB GDDR6 · Ada Lovelace
|
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|---|---|---|---|
| Specifications | |||
| Manufacturer | AMD | NVIDIA | |
| Architecture | CDNA 3 | Ada Lovelace | |
| VRAM | 256 GB HBM3e | 48 GB GDDR6 | |
| Memory Bandwidth | 6,000 GB/s | 864 GB/s | |
| FP16 (Tensor) | 1307.0 TFLOPS | 181.0 TFLOPS | |
| FP32 | 163.4 TFLOPS | 90.5 TFLOPS | |
| TDP | 1000W | 300W | |
| Release Year | 2024 | 2023 | |
| Segment | Data center | Data center | |
| Best For | AI training large model inference | Inference video processing rendering | |
| Cloud Pricing | |||
| Cheapest On-Demand | $2.00/hr | — | |
| Cheapest Spot | — | — | |
| Providers | 2 | 0 | |
| Provider Pricing (On-Demand) | |||
|
$2.00/hr | N/A | |
AMD Instinct MI325X
NVIDIA L40