AMD Instinct MI350X vs NVIDIA Tesla P4 — GPU Comparison (Jul 2026)

AMD Instinct MI350X (288GB HBM3e, 1,800 TFLOPS FP16, CDNA 4) vs NVIDIA Tesla P4 (8GB GDDR5, Pascal). Cloud pricing: NVIDIA Tesla P4 from $0.16/hr. Compare specs, VRAM, performance, and pricing across 1 cloud providers to find the best GPU for your AI workload.

Bottom Line: AMD Instinct MI350X vs NVIDIA Tesla P4

AMD Instinct MI350X comes out ahead overall, leading in 4 of 5 compared categories.

Where AMD Instinct MI350X leads

  • VRAM (288 GB vs 8 GB)
  • Memory Bandwidth (8,000 GB/s vs 192 GB/s)
  • FP32 (72 TFLOPS vs 5.5 TFLOPS)
  • Release Year (2025 vs 2016)

Where NVIDIA Tesla P4 leads

  • TDP (75W vs 1000W)

Choose AMD Instinct MI350X for Next-gen AI training, inference at scale. Choose NVIDIA Tesla P4 for Legacy inference, video transcoding.

Frequently Asked Questions

Is AMD Instinct MI350X or NVIDIA Tesla P4 better?
AMD Instinct MI350X leads in 4 of 5 compared categories. The right choice still depends on the factors that matter most to you.
Which has a better VRAM, AMD Instinct MI350X or NVIDIA Tesla P4?
AMD Instinct MI350X (288 GB vs 8 GB).
Which has a better Memory Bandwidth, AMD Instinct MI350X or NVIDIA Tesla P4?
AMD Instinct MI350X (8,000 GB/s vs 192 GB/s).
AMD Instinct MI350X vs NVIDIA Tesla P4 — GPU Comparison (Jul 2026)
AMD Instinct MI350X
288GB HBM3e · CDNA 4
View AMD Instinct MI350X Pricing
NVIDIA Tesla P4
8GB GDDR5 · Pascal
View NVIDIA Tesla P4 Pricing
Specifications
Manufacturer AMD NVIDIA
Architecture CDNA 4 Pascal
VRAM 288 GB HBM3e 8 GB GDDR5
Memory Bandwidth 8,000 GB/s 192 GB/s
FP16 (Tensor) 1800.0 TFLOPS N/A
FP32 72.0 TFLOPS 5.5 TFLOPS
TDP 1000W 75W
Release Year 2025 2016
Segment Data center Data center
Best For Next-gen AI training inference at scale Legacy inference video transcoding
Cloud Pricing
Cheapest On-Demand $0.16/hr
Cheapest Spot
Providers 1 1
Provider Pricing (On-Demand)
Cherry Servers N/A $0.16/hr
AMD Instinct MI350X NVIDIA Tesla P4