AMD Instinct MI350X vs NVIDIA GeForce RTX 4080 SUPER — GPU Comparison (Apr 2026)

AMD Instinct MI350X (288GB HBM3e, 1,800 TFLOPS FP16, CDNA 4) vs NVIDIA GeForce RTX 4080 SUPER (16GB GDDR6X, 52.4 TFLOPS FP16, Ada Lovelace)

AMD Instinct MI350X vs NVIDIA GeForce RTX 4080 SUPER — GPU Comparison (Apr 2026)
AMD Instinct MI350X
288GB HBM3e · CDNA 4
View AMD Instinct MI350X Pricing
NVIDIA GeForce RTX 4080 SUPER
16GB GDDR6X · Ada Lovelace
View NVIDIA GeForce RTX 4080 SUPER Pricing
Specifications
Manufacturer AMD NVIDIA
Architecture CDNA 4 Ada Lovelace
VRAM 288 GB HBM3e 16 GB GDDR6X
Memory Bandwidth 8,000 GB/s 736 GB/s
FP16 (Tensor) 1800.0 TFLOPS 52.4 TFLOPS
FP32 72.0 TFLOPS 26.2 TFLOPS
TDP 1000W 320W
Release Year 2025 2024
Segment Data center Consumer
Best For Next-gen AI training inference at scale Gaming inference fine-tuning
Cloud Pricing
Cheapest On-Demand
Cheapest Spot
Providers 1 0
AMD Instinct MI350X NVIDIA GeForce RTX 4080 SUPER