AMD Instinct MI325X vs NVIDIA RTX A4000 — GPU Comparison (Jul 2026)
AMD Instinct MI325X (256GB HBM3e, 1,307 TFLOPS FP16, CDNA 3) vs NVIDIA RTX A4000 (16GB GDDR6, 19.2 TFLOPS FP16, Ampere). Cloud pricing: AMD Instinct MI325X from $2.00/hr. Compare specs, VRAM, performance, and pricing across 1 cloud providers to find the best GPU for your AI workload.
Bottom Line: AMD Instinct MI325X vs NVIDIA RTX A4000
AMD Instinct MI325X comes out ahead overall, leading in 5 of 6 compared categories.
Where AMD Instinct MI325X leads
- FP16 (1,307 TFLOPS vs 19.2 TFLOPS)
- VRAM (256 GB vs 16 GB)
- Memory Bandwidth (6,000 GB/s vs 448 GB/s)
- FP32 (163.4 TFLOPS vs 16 TFLOPS)
- Release Year (2024 vs 2021)
Where NVIDIA RTX A4000 leads
- TDP (140W vs 1000W)
Choose AMD Instinct MI325X for AI training, large model inference. Choose NVIDIA RTX A4000 for Entry workstation, rendering.
Frequently Asked Questions
Is AMD Instinct MI325X or NVIDIA RTX A4000 better?
AMD Instinct MI325X leads in 5 of 6 compared categories. The right choice still depends on the factors that matter most to you.
Which has a better FP16, AMD Instinct MI325X or NVIDIA RTX A4000?
AMD Instinct MI325X (1,307 TFLOPS vs 19.2 TFLOPS).
Which has a better VRAM, AMD Instinct MI325X or NVIDIA RTX A4000?
AMD Instinct MI325X (256 GB vs 16 GB).
|
AMD Instinct MI325X
256GB HBM3e · CDNA 3
|
NVIDIA RTX A4000
16GB GDDR6 · Ampere
|
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|---|---|---|---|
| Specifications | |||
| Manufacturer | AMD | NVIDIA | |
| Architecture | CDNA 3 | Ampere | |
| VRAM | 256 GB HBM3e | 16 GB GDDR6 | |
| Memory Bandwidth | 6,000 GB/s | 448 GB/s | |
| FP16 (Tensor) | 1307.0 TFLOPS | 19.2 TFLOPS | |
| FP32 | 163.4 TFLOPS | 16.0 TFLOPS | |
| TDP | 1000W | 140W | |
| Release Year | 2024 | 2021 | |
| Segment | Data center | Professional | |
| Best For | AI training large model inference | Entry workstation rendering | |
| Cloud Pricing | |||
| Cheapest On-Demand | $2.00/hr | — | |
| Cheapest Spot | — | — | |
| Providers | 2 | 0 | |
| Provider Pricing (On-Demand) | |||
|
$2.00/hr | N/A | |
AMD Instinct MI325X
NVIDIA RTX A4000