AMD Instinct MI325X vs NVIDIA RTX 4500 Ada — GPU Comparison (Apr 2026)
AMD Instinct MI325X (256GB HBM3e, 1,307 TFLOPS FP16, CDNA 3) vs NVIDIA RTX 4500 Ada (24GB GDDR6, 31.7 TFLOPS FP16, Ada Lovelace). Cloud pricing: AMD Instinct MI325X from $2.00/hr. Compare specs, VRAM, performance, and pricing across 1 cloud providers to find the best GPU for your AI workload.
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AMD Instinct MI325X
256GB HBM3e · CDNA 3
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NVIDIA RTX 4500 Ada
24GB GDDR6 · Ada Lovelace
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| Specifications | |||
| Manufacturer | AMD | NVIDIA | |
| Architecture | CDNA 3 | Ada Lovelace | |
| VRAM | 256 GB HBM3e | 24 GB GDDR6 | |
| Memory Bandwidth | 6,000 GB/s | 432 GB/s | |
| FP16 (Tensor) | 1307.0 TFLOPS | 31.7 TFLOPS | |
| FP32 | 163.4 TFLOPS | 23.8 TFLOPS | |
| TDP | 1000W | 210W | |
| Release Year | 2024 | 2024 | |
| Segment | Data center | Professional | |
| Best For | AI training large model inference | CAD visualization light AI | |
| Cloud Pricing | |||
| Cheapest On-Demand | $2.00/hr | — | |
| Cheapest Spot | — | — | |
| Providers | 2 | 0 | |
| Provider Pricing (On-Demand) | |||
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$2.00/hr | N/A | |
AMD Instinct MI325X
NVIDIA RTX 4500 Ada