AMD Instinct MI325X vs NVIDIA RTX 4500 Ada — GPU Comparison (Jul 2026)
AMD Instinct MI325X (256GB HBM3e, 1,307 TFLOPS FP16, CDNA 3) vs NVIDIA RTX 4500 Ada (24GB GDDR6, 31.7 TFLOPS FP16, Ada Lovelace). Cloud pricing: AMD Instinct MI325X from $2.00/hr. Compare specs, VRAM, performance, and pricing across 1 cloud providers to find the best GPU for your AI workload.
Bottom Line: AMD Instinct MI325X vs NVIDIA RTX 4500 Ada
AMD Instinct MI325X comes out ahead overall, leading in 4 of 5 compared categories.
Where AMD Instinct MI325X leads
- FP16 (1,307 TFLOPS vs 31.7 TFLOPS)
- VRAM (256 GB vs 24 GB)
- Memory Bandwidth (6,000 GB/s vs 432 GB/s)
- FP32 (163.4 TFLOPS vs 23.8 TFLOPS)
Where NVIDIA RTX 4500 Ada leads
- TDP (210W vs 1000W)
Choose AMD Instinct MI325X for AI training, large model inference. Choose NVIDIA RTX 4500 Ada for CAD, visualization, light AI.
Frequently Asked Questions
Is AMD Instinct MI325X or NVIDIA RTX 4500 Ada better?
AMD Instinct MI325X leads in 4 of 5 compared categories. The right choice still depends on the factors that matter most to you.
Which has a better FP16, AMD Instinct MI325X or NVIDIA RTX 4500 Ada?
AMD Instinct MI325X (1,307 TFLOPS vs 31.7 TFLOPS).
Which has a better VRAM, AMD Instinct MI325X or NVIDIA RTX 4500 Ada?
AMD Instinct MI325X (256 GB vs 24 GB).
|
AMD Instinct MI325X
256GB HBM3e · CDNA 3
|
NVIDIA RTX 4500 Ada
24GB GDDR6 · Ada Lovelace
|
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|---|---|---|---|
| Specifications | |||
| Manufacturer | AMD | NVIDIA | |
| Architecture | CDNA 3 | Ada Lovelace | |
| VRAM | 256 GB HBM3e | 24 GB GDDR6 | |
| Memory Bandwidth | 6,000 GB/s | 432 GB/s | |
| FP16 (Tensor) | 1307.0 TFLOPS | 31.7 TFLOPS | |
| FP32 | 163.4 TFLOPS | 23.8 TFLOPS | |
| TDP | 1000W | 210W | |
| Release Year | 2024 | 2024 | |
| Segment | Data center | Professional | |
| Best For | AI training large model inference | CAD visualization light AI | |
| Cloud Pricing | |||
| Cheapest On-Demand | $2.00/hr | — | |
| Cheapest Spot | — | — | |
| Providers | 2 | 0 | |
| Provider Pricing (On-Demand) | |||
|
$2.00/hr | N/A | |
AMD Instinct MI325X
NVIDIA RTX 4500 Ada