AMD Instinct MI325X vs NVIDIA B300 — GPU Comparison (Apr 2026)
AMD Instinct MI325X (256GB HBM3e, 1,307 TFLOPS FP16, CDNA 3) vs NVIDIA B300 (288GB HBM3e, 2,250 TFLOPS FP16, Blackwell Ultra). Cloud pricing: AMD Instinct MI325X from $2.00/hr. Compare specs, VRAM, performance, and pricing across 1 cloud providers to find the best GPU for your AI workload.
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AMD Instinct MI325X
256GB HBM3e · CDNA 3
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NVIDIA B300
288GB HBM3e · Blackwell Ultra
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| Specifications | |||
| Manufacturer | AMD | NVIDIA | |
| Architecture | CDNA 3 | Blackwell Ultra | |
| VRAM | 256 GB HBM3e | 288 GB HBM3e | |
| Memory Bandwidth | 6,000 GB/s | 8,000 GB/s | |
| FP16 (Tensor) | 1307.0 TFLOPS | 2250.0 TFLOPS | |
| FP32 | 163.4 TFLOPS | 75.0 TFLOPS | |
| TDP | 1000W | 1400W | |
| Release Year | 2024 | 2025 | |
| Segment | Data center | Data center | |
| Best For | AI training large model inference | Frontier AI training largest model workloads | |
| Cloud Pricing | |||
| Cheapest On-Demand | $2.00/hr | — | |
| Cheapest Spot | — | — | |
| Providers | 2 | 1 | |
| Provider Pricing (On-Demand) | |||
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$2.00/hr | N/A | |
AMD Instinct MI325X
NVIDIA B300