AMD Instinct MI325X vs NVIDIA B100 — GPU Comparison (Jul 2026)
AMD Instinct MI325X (256GB HBM3e, 1,307 TFLOPS FP16, CDNA 3) vs NVIDIA B100 (192GB HBM3e, 1,750 TFLOPS FP16, Blackwell). Cloud pricing: AMD Instinct MI325X from $2.00/hr. Compare specs, VRAM, performance, and pricing across 1 cloud providers to find the best GPU for your AI workload.
Bottom Line: AMD Instinct MI325X vs NVIDIA B100
NVIDIA B100 comes out ahead overall, leading in 3 of 5 compared categories.
Where AMD Instinct MI325X leads
- VRAM (256 GB vs 192 GB)
- FP32 (163.4 TFLOPS vs 60 TFLOPS)
Where NVIDIA B100 leads
- FP16 (1,750 TFLOPS vs 1,307 TFLOPS)
- Memory Bandwidth (8,000 GB/s vs 6,000 GB/s)
- TDP (700W vs 1000W)
Choose AMD Instinct MI325X for AI training, large model inference. Choose NVIDIA B100 for AI training, large-scale inference.
Frequently Asked Questions
Is AMD Instinct MI325X or NVIDIA B100 better?
NVIDIA B100 leads in 3 of 5 compared categories. The right choice still depends on the factors that matter most to you.
Which has a better FP16, AMD Instinct MI325X or NVIDIA B100?
NVIDIA B100 (1,750 TFLOPS vs 1,307 TFLOPS).
Which has a better VRAM, AMD Instinct MI325X or NVIDIA B100?
AMD Instinct MI325X (256 GB vs 192 GB).
|
AMD Instinct MI325X
256GB HBM3e · CDNA 3
|
NVIDIA B100
192GB HBM3e · Blackwell
|
||
|---|---|---|---|
| Specifications | |||
| Manufacturer | AMD | NVIDIA | |
| Architecture | CDNA 3 | Blackwell | |
| VRAM | 256 GB HBM3e | 192 GB HBM3e | |
| Memory Bandwidth | 6,000 GB/s | 8,000 GB/s | |
| FP16 (Tensor) | 1307.0 TFLOPS | 1750.0 TFLOPS | |
| FP32 | 163.4 TFLOPS | 60.0 TFLOPS | |
| TDP | 1000W | 700W | |
| Release Year | 2024 | 2024 | |
| Segment | Data center | Data center | |
| Best For | AI training large model inference | AI training large-scale inference | |
| Cloud Pricing | |||
| Cheapest On-Demand | $2.00/hr | — | |
| Cheapest Spot | — | — | |
| Providers | 2 | 0 | |
| Provider Pricing (On-Demand) | |||
|
$2.00/hr | N/A | |
AMD Instinct MI325X
NVIDIA B100