AMD Instinct MI325X vs AMD Instinct MI350X — GPU Comparison (Jul 2026)
AMD Instinct MI325X (256GB HBM3e, 1,307 TFLOPS FP16, CDNA 3) vs AMD Instinct MI350X (288GB HBM3e, 1,800 TFLOPS FP16, CDNA 4). Cloud pricing: AMD Instinct MI325X from $2.00/hr. Compare specs, VRAM, performance, and pricing across 1 cloud providers to find the best GPU for your AI workload.
Bottom Line: AMD Instinct MI325X vs AMD Instinct MI350X
AMD Instinct MI350X comes out ahead overall, leading in 4 of 5 compared categories.
Where AMD Instinct MI325X leads
- FP32 (163.4 TFLOPS vs 72 TFLOPS)
Where AMD Instinct MI350X leads
- FP16 (1,800 TFLOPS vs 1,307 TFLOPS)
- VRAM (288 GB vs 256 GB)
- Memory Bandwidth (8,000 GB/s vs 6,000 GB/s)
- Release Year (2025 vs 2024)
Choose AMD Instinct MI325X for AI training, large model inference. Choose AMD Instinct MI350X for Next-gen AI training, inference at scale.
Frequently Asked Questions
Is AMD Instinct MI325X or AMD Instinct MI350X better?
AMD Instinct MI350X leads in 4 of 5 compared categories. The right choice still depends on the factors that matter most to you.
Which has a better FP16, AMD Instinct MI325X or AMD Instinct MI350X?
AMD Instinct MI350X (1,800 TFLOPS vs 1,307 TFLOPS).
Which has a better VRAM, AMD Instinct MI325X or AMD Instinct MI350X?
AMD Instinct MI350X (288 GB vs 256 GB).
|
AMD Instinct MI325X
256GB HBM3e · CDNA 3
|
AMD Instinct MI350X
288GB HBM3e · CDNA 4
|
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|---|---|---|---|
| Specifications | |||
| Manufacturer | AMD | AMD | |
| Architecture | CDNA 3 | CDNA 4 | |
| VRAM | 256 GB HBM3e | 288 GB HBM3e | |
| Memory Bandwidth | 6,000 GB/s | 8,000 GB/s | |
| FP16 (Tensor) | 1307.0 TFLOPS | 1800.0 TFLOPS | |
| FP32 | 163.4 TFLOPS | 72.0 TFLOPS | |
| TDP | 1000W | 1000W | |
| Release Year | 2024 | 2025 | |
| Segment | Data center | Data center | |
| Best For | AI training large model inference | Next-gen AI training inference at scale | |
| Cloud Pricing | |||
| Cheapest On-Demand | $2.00/hr | — | |
| Cheapest Spot | — | — | |
| Providers | 2 | 1 | |
| Provider Pricing (On-Demand) | |||
|
$2.00/hr | N/A | |
AMD Instinct MI325X
AMD Instinct MI350X
