AMD Instinct MI355X vs NVIDIA GeForce RTX 4060 — GPU Comparison (Jul 2026)

AMD Instinct MI355X (288GB HBM3e, 1,800 TFLOPS FP16, CDNA 4) vs NVIDIA GeForce RTX 4060 (8GB GDDR6, 15.1 TFLOPS FP16, Ada Lovelace). Cloud pricing: AMD Instinct MI355X from $2.59/hr. Compare specs, VRAM, performance, and pricing across 1 cloud providers to find the best GPU for your AI workload.

Bottom Line: AMD Instinct MI355X vs NVIDIA GeForce RTX 4060

AMD Instinct MI355X comes out ahead overall, leading in 5 of 6 compared categories.

Where AMD Instinct MI355X leads

  • FP16 (1,800 TFLOPS vs 15.1 TFLOPS)
  • VRAM (288 GB vs 8 GB)
  • Memory Bandwidth (8,000 GB/s vs 272 GB/s)
  • FP32 (72 TFLOPS vs 7.6 TFLOPS)
  • Release Year (2025 vs 2023)

Where NVIDIA GeForce RTX 4060 leads

  • TDP (115W vs 1400W)

Choose AMD Instinct MI355X for Frontier AI training, highest-end AMD workloads. Choose NVIDIA GeForce RTX 4060 for Entry-level inference, gaming.

Frequently Asked Questions

Is AMD Instinct MI355X or NVIDIA GeForce RTX 4060 better?
AMD Instinct MI355X leads in 5 of 6 compared categories. The right choice still depends on the factors that matter most to you.
Which has a better FP16, AMD Instinct MI355X or NVIDIA GeForce RTX 4060?
AMD Instinct MI355X (1,800 TFLOPS vs 15.1 TFLOPS).
Which has a better VRAM, AMD Instinct MI355X or NVIDIA GeForce RTX 4060?
AMD Instinct MI355X (288 GB vs 8 GB).
AMD Instinct MI355X vs NVIDIA GeForce RTX 4060 — GPU Comparison (Jul 2026)
AMD Instinct MI355X
288GB HBM3e · CDNA 4
View AMD Instinct MI355X Pricing
NVIDIA GeForce RTX 4060
8GB GDDR6 · Ada Lovelace
View NVIDIA GeForce RTX 4060 Pricing
Specifications
Manufacturer AMD NVIDIA
Architecture CDNA 4 Ada Lovelace
VRAM 288 GB HBM3e 8 GB GDDR6
Memory Bandwidth 8,000 GB/s 272 GB/s
FP16 (Tensor) 1800.0 TFLOPS 15.1 TFLOPS
FP32 72.0 TFLOPS 7.6 TFLOPS
TDP 1400W 115W
Release Year 2025 2023
Segment Data center Consumer
Best For Frontier AI training highest-end AMD workloads Entry-level inference gaming
Cloud Pricing
Cheapest On-Demand $2.59/hr
Cheapest Spot
Providers 1 0
Provider Pricing (On-Demand)
Vultr $2.59/hr N/A
AMD Instinct MI355X NVIDIA GeForce RTX 4060