AMD Instinct MI355X vs NVIDIA GeForce RTX 4060 Ti — GPU Comparison (Jul 2026)

AMD Instinct MI355X (288GB HBM3e, 1,800 TFLOPS FP16, CDNA 4) vs NVIDIA GeForce RTX 4060 Ti (16GB GDDR6, 22.1 TFLOPS FP16, Ada Lovelace). Cloud pricing: AMD Instinct MI355X from $2.59/hr. Compare specs, VRAM, performance, and pricing across 1 cloud providers to find the best GPU for your AI workload.

Bottom Line: AMD Instinct MI355X vs NVIDIA GeForce RTX 4060 Ti

AMD Instinct MI355X comes out ahead overall, leading in 5 of 6 compared categories.

Where AMD Instinct MI355X leads

  • FP16 (1,800 TFLOPS vs 22.1 TFLOPS)
  • VRAM (288 GB vs 16 GB)
  • Memory Bandwidth (8,000 GB/s vs 288 GB/s)
  • FP32 (72 TFLOPS vs 11 TFLOPS)
  • Release Year (2025 vs 2023)

Where NVIDIA GeForce RTX 4060 Ti leads

  • TDP (165W vs 1400W)

Choose AMD Instinct MI355X for Frontier AI training, highest-end AMD workloads. Choose NVIDIA GeForce RTX 4060 Ti for Budget inference, gaming.

Frequently Asked Questions

Is AMD Instinct MI355X or NVIDIA GeForce RTX 4060 Ti better?
AMD Instinct MI355X leads in 5 of 6 compared categories. The right choice still depends on the factors that matter most to you.
Which has a better FP16, AMD Instinct MI355X or NVIDIA GeForce RTX 4060 Ti?
AMD Instinct MI355X (1,800 TFLOPS vs 22.1 TFLOPS).
Which has a better VRAM, AMD Instinct MI355X or NVIDIA GeForce RTX 4060 Ti?
AMD Instinct MI355X (288 GB vs 16 GB).
AMD Instinct MI355X vs NVIDIA GeForce RTX 4060 Ti — GPU Comparison (Jul 2026)
AMD Instinct MI355X
288GB HBM3e · CDNA 4
View AMD Instinct MI355X Pricing
NVIDIA GeForce RTX 4060 Ti
16GB GDDR6 · Ada Lovelace
View NVIDIA GeForce RTX 4060 Ti Pricing
Specifications
Manufacturer AMD NVIDIA
Architecture CDNA 4 Ada Lovelace
VRAM 288 GB HBM3e 16 GB GDDR6
Memory Bandwidth 8,000 GB/s 288 GB/s
FP16 (Tensor) 1800.0 TFLOPS 22.1 TFLOPS
FP32 72.0 TFLOPS 11.0 TFLOPS
TDP 1400W 165W
Release Year 2025 2023
Segment Data center Consumer
Best For Frontier AI training highest-end AMD workloads Budget inference gaming
Cloud Pricing
Cheapest On-Demand $2.59/hr
Cheapest Spot
Providers 1 0
Provider Pricing (On-Demand)
Vultr $2.59/hr N/A
AMD Instinct MI355X NVIDIA GeForce RTX 4060 Ti