AMD Instinct MI355X vs NVIDIA GeForce RTX 3080 — GPU Comparison (Jul 2026)

AMD Instinct MI355X (288GB HBM3e, 1,800 TFLOPS FP16, CDNA 4) vs NVIDIA GeForce RTX 3080 (10GB GDDR6X, 29.8 TFLOPS FP16, Ampere). Cloud pricing: AMD Instinct MI355X from $2.59/hr. Compare specs, VRAM, performance, and pricing across 1 cloud providers to find the best GPU for your AI workload.

Bottom Line: AMD Instinct MI355X vs NVIDIA GeForce RTX 3080

AMD Instinct MI355X comes out ahead overall, leading in 5 of 6 compared categories.

Where AMD Instinct MI355X leads

  • FP16 (1,800 TFLOPS vs 29.8 TFLOPS)
  • VRAM (288 GB vs 10 GB)
  • Memory Bandwidth (8,000 GB/s vs 760 GB/s)
  • FP32 (72 TFLOPS vs 14.9 TFLOPS)
  • Release Year (2025 vs 2020)

Where NVIDIA GeForce RTX 3080 leads

  • TDP (320W vs 1400W)

Choose AMD Instinct MI355X for Frontier AI training, highest-end AMD workloads. Choose NVIDIA GeForce RTX 3080 for Gaming, inference.

Frequently Asked Questions

Is AMD Instinct MI355X or NVIDIA GeForce RTX 3080 better?
AMD Instinct MI355X leads in 5 of 6 compared categories. The right choice still depends on the factors that matter most to you.
Which has a better FP16, AMD Instinct MI355X or NVIDIA GeForce RTX 3080?
AMD Instinct MI355X (1,800 TFLOPS vs 29.8 TFLOPS).
Which has a better VRAM, AMD Instinct MI355X or NVIDIA GeForce RTX 3080?
AMD Instinct MI355X (288 GB vs 10 GB).
AMD Instinct MI355X vs NVIDIA GeForce RTX 3080 — GPU Comparison (Jul 2026)
AMD Instinct MI355X
288GB HBM3e · CDNA 4
View AMD Instinct MI355X Pricing
NVIDIA GeForce RTX 3080
10GB GDDR6X · Ampere
View NVIDIA GeForce RTX 3080 Pricing
Specifications
Manufacturer AMD NVIDIA
Architecture CDNA 4 Ampere
VRAM 288 GB HBM3e 10 GB GDDR6X
Memory Bandwidth 8,000 GB/s 760 GB/s
FP16 (Tensor) 1800.0 TFLOPS 29.8 TFLOPS
FP32 72.0 TFLOPS 14.9 TFLOPS
TDP 1400W 320W
Release Year 2025 2020
Segment Data center Consumer
Best For Frontier AI training highest-end AMD workloads Gaming inference
Cloud Pricing
Cheapest On-Demand $2.59/hr
Cheapest Spot
Providers 1 0
Provider Pricing (On-Demand)
Vultr $2.59/hr N/A
AMD Instinct MI355X NVIDIA GeForce RTX 3080