AMD Instinct MI355X vs NVIDIA GH200 Superchip — GPU Comparison (Jul 2026)

AMD Instinct MI355X (288GB HBM3e, 1,800 TFLOPS FP16, CDNA 4) vs NVIDIA GH200 Superchip (96GB HBM3, 989 TFLOPS FP16, Hopper). Cloud pricing: AMD Instinct MI355X from $2.59/hr. Compare specs, VRAM, performance, and pricing across 1 cloud providers to find the best GPU for your AI workload.

Bottom Line: AMD Instinct MI355X vs NVIDIA GH200 Superchip

AMD Instinct MI355X comes out ahead overall, leading in 4 of 6 compared categories.

Where AMD Instinct MI355X leads

  • FP16 (1,800 TFLOPS vs 989 TFLOPS)
  • VRAM (288 GB vs 96 GB)
  • Memory Bandwidth (8,000 GB/s vs 4,000 GB/s)
  • Release Year (2025 vs 2023)

Where NVIDIA GH200 Superchip leads

  • FP32 (494.5 TFLOPS vs 72 TFLOPS)
  • TDP (700W vs 1400W)

Choose AMD Instinct MI355X for Frontier AI training, highest-end AMD workloads. Choose NVIDIA GH200 Superchip for Large-scale AI training, HPC.

Frequently Asked Questions

Is AMD Instinct MI355X or NVIDIA GH200 Superchip better?
AMD Instinct MI355X leads in 4 of 6 compared categories. The right choice still depends on the factors that matter most to you.
Which has a better FP16, AMD Instinct MI355X or NVIDIA GH200 Superchip?
AMD Instinct MI355X (1,800 TFLOPS vs 989 TFLOPS).
Which has a better VRAM, AMD Instinct MI355X or NVIDIA GH200 Superchip?
AMD Instinct MI355X (288 GB vs 96 GB).
AMD Instinct MI355X vs NVIDIA GH200 Superchip — GPU Comparison (Jul 2026)
AMD Instinct MI355X
288GB HBM3e · CDNA 4
View AMD Instinct MI355X Pricing
NVIDIA GH200 Superchip
96GB HBM3 · Hopper
View NVIDIA GH200 Superchip Pricing
Specifications
Manufacturer AMD NVIDIA
Architecture CDNA 4 Hopper
VRAM 288 GB HBM3e 96 GB HBM3
Memory Bandwidth 8,000 GB/s 4,000 GB/s
FP16 (Tensor) 1800.0 TFLOPS 989.0 TFLOPS
FP32 72.0 TFLOPS 494.5 TFLOPS
TDP 1400W 700W
Release Year 2025 2023
Segment Data center Data center
Best For Frontier AI training highest-end AMD workloads Large-scale AI training HPC
Cloud Pricing
Cheapest On-Demand $2.59/hr
Cheapest Spot
Providers 1 0
Provider Pricing (On-Demand)
Vultr $2.59/hr N/A
AMD Instinct MI355X NVIDIA GH200 Superchip