AMD Instinct MI350X vs NVIDIA GeForce RTX 5080 — GPU Comparison (Apr 2026)

AMD Instinct MI350X (288GB HBM3e, 1,800 TFLOPS FP16, CDNA 4) vs NVIDIA GeForce RTX 5080 (16GB GDDR7, 56 TFLOPS FP16, Blackwell)

AMD Instinct MI350X vs NVIDIA GeForce RTX 5080 — GPU Comparison (Apr 2026)
AMD Instinct MI350X
288GB HBM3e · CDNA 4
View AMD Instinct MI350X Pricing
NVIDIA GeForce RTX 5080
16GB GDDR7 · Blackwell
View NVIDIA GeForce RTX 5080 Pricing
Specifications
Manufacturer AMD NVIDIA
Architecture CDNA 4 Blackwell
VRAM 288 GB HBM3e 16 GB GDDR7
Memory Bandwidth 8,000 GB/s 960 GB/s
FP16 (Tensor) 1800.0 TFLOPS 56.0 TFLOPS
FP32 72.0 TFLOPS 28.0 TFLOPS
TDP 1000W 360W
Release Year 2025 2025
Segment Data center Consumer
Best For Next-gen AI training inference at scale Gaming inference fine-tuning
Cloud Pricing
Cheapest On-Demand
Cheapest Spot
Providers 1 0
AMD Instinct MI350X NVIDIA GeForce RTX 5080