AMD Instinct MI350X vs NVIDIA GeForce RTX 4080 — GPU Comparison (Apr 2026)
AMD Instinct MI350X (288GB HBM3e, 1,800 TFLOPS FP16, CDNA 4) vs NVIDIA GeForce RTX 4080 (16GB GDDR6X, 48.7 TFLOPS FP16, Ada Lovelace)
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AMD Instinct MI350X
288GB HBM3e · CDNA 4
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NVIDIA GeForce RTX 4080
16GB GDDR6X · Ada Lovelace
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|---|---|---|---|
| Specifications | |||
| Manufacturer | AMD | NVIDIA | |
| Architecture | CDNA 4 | Ada Lovelace | |
| VRAM | 288 GB HBM3e | 16 GB GDDR6X | |
| Memory Bandwidth | 8,000 GB/s | 717 GB/s | |
| FP16 (Tensor) | 1800.0 TFLOPS | 48.7 TFLOPS | |
| FP32 | 72.0 TFLOPS | 24.4 TFLOPS | |
| TDP | 1000W | 320W | |
| Release Year | 2025 | 2022 | |
| Segment | Data center | Consumer | |
| Best For | Next-gen AI training inference at scale | Gaming inference fine-tuning | |
| Cloud Pricing | |||
| Cheapest On-Demand | — | — | |
| Cheapest Spot | — | — | |
| Providers | 1 | 0 | |
AMD Instinct MI350X
NVIDIA GeForce RTX 4080