AMD Instinct MI300X vs NVIDIA A100 SXM (80GB) — GPU Comparison (Apr 2026)
AMD Instinct MI300X (192GB HBM3, 1,307 TFLOPS FP16, CDNA 3) vs NVIDIA A100 SXM (80GB) (80GB HBM2e, 312 TFLOPS FP16, Ampere). Cloud pricing: AMD Instinct MI300X from $1.85/hr, NVIDIA A100 SXM (80GB) from $1.10/hr. Compare specs, VRAM, performance, and pricing across 7 cloud providers to find the best GPU for your AI workload.
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AMD Instinct MI300X
192GB HBM3 · CDNA 3
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NVIDIA A100 SXM (80GB)
80GB HBM2e · Ampere
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| Specifications | |||
| Manufacturer | AMD | NVIDIA | |
| Architecture | CDNA 3 | Ampere | |
| VRAM | 192 GB HBM3 | 80 GB HBM2e | |
| Memory Bandwidth | 5,300 GB/s | 2,039 GB/s | |
| FP16 (Tensor) | 1307.0 TFLOPS | 312.0 TFLOPS | |
| FP32 | 163.4 TFLOPS | 19.5 TFLOPS | |
| TDP | 750W | 400W | |
| Release Year | 2023 | 2020 | |
| Segment | Data center | Data center | |
| Best For | Large-scale AI training LLM inference HPC | AI training fine-tuning HPC inference | |
| Cloud Pricing | |||
| Cheapest On-Demand | $1.85/hr | $1.10/hr | |
| Cheapest Spot | — | $0.79/hr | |
| Providers | 2 | 6 | |
| Provider Pricing (On-Demand) | |||
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$1.85/hr | $2.40/hr | |
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$1.99/hr | N/A | |
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N/A | $1.10/hr | |
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N/A | $1.23/hr | |
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N/A | $1.49/hr | |
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N/A | $1.60/hr | |
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N/A | $2.18/hr | |
AMD Instinct MI300X
NVIDIA A100 SXM (80GB)
Related GPU Comparisons
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Top Providers for AMD Instinct MI300X and NVIDIA A100 SXM (80GB)
These 3 providers offer both AMD Instinct MI300X and NVIDIA A100 SXM (80GB). Full head-to-head comparison of GPU models, pricing, infrastructure, and developer tools.
Vast.ai vs Massed Compute vs RunPod - GPU Provider Comparison (April 2026)
Side-by-side comparison of Vast.ai vs Massed Compute vs RunPod. Quickly compare GPU models, hourly pricing, spot instances, billing granularity, VRAM, regions, developer tools, Kubernetes support, and compliance to narrow down your cloud GPU provider shortlist. Data updated April 2026.
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Vast.ai
Instant GPUs. Transparent Pricing.
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Massed Compute
GPU cloud with direct engineer support
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RunPod
The cloud built for AI — deploy and scale GPU workloads from serverless inference to instant multi-node clusters on demand.
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|---|---|---|---|
| Overview | |||
| Trustpilot Rating | 4.4 | 0 | 3.7 |
| Headquarters | United States | United States | United States |
| Provider Type | GPU Marketplace | GPU-Focused | GPU-Focused |
| Best For | AI training inference fine-tuning Stable Diffusion batch processing research LLM serving generative AI | AI training inference VFX rendering generative AI fine-tuning HPC Stable Diffusion research | AI training inference fine-tuning Stable Diffusion batch processing rendering research LLM serving generative AI |
| GPU Hardware | |||
| GPU Models | B200 H200 H100 SXM H100 NVL A100 SXM A100 PCIe RTX 5090 RTX 5080 RTX 5070 Ti RTX 6000 Pro RTX 6000 Ada RTX 4500 Ada RTX A6000 RTX A5000 RTX A4000 L40S L40 A40 A10 RTX 4090 RTX 4080 RTX 4070 Ti RTX 4070 RTX 4060 Ti RTX 4060 RTX 3090 Ti RTX 3090 RTX 3080 Ti RTX 3080 RTX 3070 Ti RTX 3070 Tesla V100 Tesla T4 A2 GTX 1080 | A30 RTX A5000 RTX A6000 L40S A100 SXM H100 PCIe H100 SXM H100 NVL RTX PRO 6000 H200 NVL | B300 B200 H200 H100 SXM H100 PCIe H100 NVL MI300X A100 SXM A100 PCIe RTX 5090 RTX PRO 6000 L40S L40 RTX 6000 Ada RTX 5000 Ada RTX A6000 RTX A5000 RTX 4090 RTX 4080 SUPER RTX 4080 RTX 4070 Ti RTX 3090 Ti RTX 3090 RTX 3080 Ti RTX 3080 RTX 3070 A40 A30 A2 L4 |
| Max VRAM (GB) | 192 | 141 | 288 |
| Max GPUs/Instance | 8 | 8 | 8 |
| Interconnect | NVLink, InfiniBand | NVLink | NVLink |
| Pricing | |||
| Starting Price ($/hr) | $0.06/hr | $0.35/hr | $0.06/hr |
| Billing Granularity | Per-second | Per-minute | Per-second |
| Spot/Preemptible | Yes | No | Yes |
| Reserved Discounts | Up to 50% (1-6 month reserved) | N/A | 15-29% (1-month to 1-year plans) |
| Free Credits | Small test credit on signup | None | $5-$500 bonus after first $10 spend |
| Egress Fees | Varies by host ($/TB) | None | None (Free) |
| Storage | Varies by host ($/GB/hr, charged while instance exists) | Local NVMe included with instances | Container/Volume ($0.10/GB/mo), Idle Volume ($0.20/GB/mo), Network Storage ($0.07/GB/mo 1TB) |
| Infrastructure | |||
| Regions | 500+ locations, 40+ data centers | United States (Tier III data centers) | 31 global regions |
| Uptime SLA | No formal SLA (host reliability scores visible) | Tier III (99.98% design) | 99.99% |
| Developer Experience | |||
| Frameworks | PyTorch TensorFlow CUDA vLLM ComfyUI | PyTorch TensorFlow CUDA cuDNN ComfyUI pre-configured ML templates | PyTorch TensorFlow JAX ONNX CUDA |
| Docker Support | Yes | Yes | Yes |
| SSH Access | Yes | Yes | Yes |
| Jupyter Notebooks | Yes | No | Yes |
| API / CLI | Yes | Yes | Yes |
| Setup Time | Seconds | Minutes | Instant |
| Kubernetes Support | No | No | No |
| Business Terms | |||
| Min Commitment | None | None | None |
| Compliance | SOC 2 Type 2 HIPAA GDPR CCPA | SOC 2 Type II HIPAA | SOC 2 Type II |
Vast.ai
Massed Compute
RunPod
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